Publications by authors named "A Gotzamani-Psarrakou"
: Despite the increasing use of biomarkers, differentiation between Alzheimer's disease (AD), behavioral variant Frontotemporal Dementia (bvFTD), and Primary Progressive Aphasia (PPA) remains a challenge. Apraxia is a supportive feature for diagnosing AD but is underrepresented in other dementia types. Herein, we investigated the presence and characteristic profiles of limb, verbal, and non-verbal apraxia in three major dementia types.
View Article and Find Full Text PDFOlder people are prone to frailness, present poor adherence to pharmacotherapy, and often have adverse drug effects. Therefore, it is important to develop effective and safe interventions to mitigate the burden of anxiety and depression disorders in this population. The aim of this study was to investigate the effect of vitamin D supplementation on the anxiety and depression status of elderly people with prediabetes.
View Article and Find Full Text PDFThe effect of vitamin D supplementation on glycemic status of elderly people with prediabetes: a 12-month open-label, randomized-controlled study.
Expert Rev Clin Pharmacol
January 2022
Article Synopsis
- A randomized-controlled trial was conducted to examine the effects of vitamin D supplementation on glycemic levels in elderly Greek individuals with prediabetes over a year.
- Participants received either a weekly dose of 25,000 IU of vitamin D or no supplement alongside lifestyle changes, with various health markers assessed at multiple points.
- Results showed that those taking vitamin D had significant increases in vitamin D levels and notable reductions in fasting glucose and glycated hemoglobin after 6 and 12 months compared to the baseline.
Background: Apraxia is considered a supportive feature in Alzheimer's disease (AD) patients. It has been reported that patients with frontotemporal dementia (FTD) may present apraxia, especially in the buccofacial area. The Apraxia Battery for Adults (ABA-2) is a brief and practical battery for praxis impairment and has been validated in Greek post-stroke patients.
View Article and Find Full Text PDFBackground And Objective: Cognitive reserve (CR) mediates the clinical expression of brain pathology in Alzheimer's disease, while there are much less relevant data in frontotemporal dementia (FTD). In the present study we examined whether CR, measured using the Cognitive Reserve Index (CRI), correlated with regional cerebral blood flow (rCBF) in Greek FTD patients.
Methods: Eighty FTD patients, i.