Publications by authors named "A Goolam Mahomed"
Elevated circulating hepcidin levels have been reported in patients with pulmonary artery hypertension (PAH). Hepcidin has been shown to promote proliferation of human pulmonary artery smooth muscle cells (PASMCs) in vitro, suggesting a potential role in PAH pathogenesis. However, the role of human pulmonary artery endothelial cells (PAECs) as either a source of hepcidin, or the effect of hepcidin on PAEC function is not as well described.
View Article and Find Full Text PDFBackground: Attention deficit hyperactive disorder (ADHD) is a neurodevelopmental disorder occurring in children and adults. Pharmacotherapy remains the cornerstone of ADHD treatment. Stimulants such as methylphenidate are effective and have been one of the best studied and most frequently used treatment for ADHD.
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- Climate change is causing more frequent and intense tropical cyclones in Mozambique, leading to health crises like cholera outbreaks, particularly after Cyclones Idai and Kenneth in 2019.
- A study in Cabo Delgado Province investigated factors contributing to acute watery diarrhea (AWD) and cholera, surveying 1,615 households to analyze the impact of climate disasters and armed conflict on health.
- Key risk factors identified included overcrowding, poor access to safe water, and inadequate handwashing facilities, highlighting the need for targeted climate adaptation policies to improve community health.
Introduction: Climate change is contributing to increase the frequency and severity of climate disasters in Mozambique, leading, since 2019, to extensive damage to infrastructure and displacement 1.3 million people. Aim of this study is to evaluate baseline preparedness to vector-borne and water-borne infections among households and internally displaced people exposed to climate disasters in Mozambique.
View Article and Find Full Text PDFBackground: Liver transplantation is the definitive management for severe acute liver failure refractory to supportive management, and end- stage chronic liver failure. Owing to a shortage of deceased liver donors, South Africa requires innovative techniques to broaden the donor pool.
Objectives: This study evaluated the outcomes of the Wits Transplant Unit ABO-incompatible liver transplant (ABOi-LT) programme.