Analysis of Metal-Organic Framework and Polyamide Interfaces in Membranes for Water Treatment and Antibacterial Applications.

Integrating biocidal nanoparticles (NPs) into polyamide (PA) membranes shows promise for enhancing resistance to biofouling. Incorporating techniques can tailor thin-film nanocomposite (TFN) membranes for specific water purification applications. In this study, silver-based metal-organic framework Ag-MOFs (using silver nitrate and 1,3,5-benzentricarboxylic acid as precursors) are incorporated into PA membranes via three different methods: i) incorporation, ii) dip-coating, and iii) in situ ultrasonic techniques.

Light-sensitive Ca signaling in the mammalian choroid.

The choroid is the thin, vasculature-filled layer of the eye situated between the sclera and the retina, where it serves the metabolic needs of the light-sensing photoreceptors in the retina. Illumination of the interior surface of the back of the eye (fundus) is a critical regulator of subretinal fluid homeostasis, which determines the overall shape of the eye, but it is also important for choroidal perfusion. Noted for having some of the highest blood flow rates in the body, the choroidal vasculature has been reported to lack intrinsic, intravascular pressure-induced (myogenic) autoregulatory mechanisms.

Mitochondrial small RNA alterations associated with increased lysosome activity in an Alzheimer's Disease Mouse Model uncovered by PANDORA-seq.

Emerging small noncoding RNAs (sncRNAs), including tRNA-derived small RNAs (tsRNAs) and rRNA-derived small RNAs (rsRNAs), are critical in various biological processes, such as neurological diseases. Traditional sncRNA-sequencing (seq) protocols often miss these sncRNAs due to their modifications, such as internal and terminal modifications, that can interfere with sequencing. We recently developed panoramic RNA display by overcoming RNA modification aborted sequencing (PANDORA-seq), a method enabling comprehensive detection of modified sncRNAs by overcoming the RNA modifications.

Improving the Identification of Diabetic Retinopathy and Related Conditions in the Electronic Health Record Using Natural Language Processing Methods.

Purpose: To compare the performance of 3 phenotyping methods in identifying diabetic retinopathy (DR) and related clinical conditions.

Design: Three phenotyping methods were used to identify clinical conditions including unspecified DR, nonproliferative DR (NPDR) (mild, moderate, severe), consolidated NPDR (unspecified DR or any NPDR), proliferative DR, diabetic macular edema (DME), vitreous hemorrhage, retinal detachment (RD) (tractional RD or combined tractional and rhegmatogenous RD), and neovascular glaucoma (NVG). The first method used only International Classification of Diseases, 10th Revision (ICD-10) diagnosis codes ().

Outcomes of Photorefractive Keratectomy After Corneal Graft: Brief Review.

Purpose: The purpose of this brief review is to analyze the outcomes of customized photorefractive keratectomy in the correction of refractive errors and irregular astigmatism after corneal graft surgery.

Methods: Two reviewers (M.S.