Publications by authors named "A Goncalves-Ferreira"
Objective: Short-term outcomes of deep brain stimulation of the anterior nucleus of the thalamus (ANT-DBS) were reported for people with drug-resistant focal epilepsy (PwE). Because long-term data are still scarce, the Medtronic Registry for Epilepsy (MORE) evaluated clinical routine application of ANT-DBS.
Methods: In this multicenter registry, PwE with ANT-DBS were followed up for safety, efficacy, and battery longevity.
Background And Objectives: The efficacy of deep brain stimulation of the anterior nucleus of the thalamus (ANT DBS) in patients with drug-resistant epilepsy (DRE) was demonstrated in the double-blind Stimulation of the Anterior Nucleus of the Thalamus for Epilepsy randomized controlled trial. The Medtronic Registry for Epilepsy (MORE) aims to understand the safety and longer-term effectiveness of ANT DBS therapy in routine clinical practice.
Methods: MORE is an observational registry collecting prospective and retrospective clinical data.
Liraglutide is a long-acting glucagon-like peptide-1 receptor agonist prescribed to diabetic patients for glycaemic control. To understand the impact of liraglutide in the real-world setting, this study analysed its effects in a Portuguese cohort of Type 2 diabetes patients. This was an observational, multicentric, and retrospective study that included 191 liraglutide-treated patients with at least 12 months of treatment.
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- The research involved 850 adults from nine international epilepsy centers, focusing on those who were seizure-free besides minor types before withdrawing medication post-surgery.
- Predictive models were created to determine the risk of seizures returning, with key factors being certain types of seizures after surgery, prior history of specific seizures, the timing of medication withdrawal, and the number of meds taken at surgery, showing a moderate level of accuracy in predicting outcomes.