Publications by authors named "A Gokcay Canpolat"

Article Synopsis
  • * The study involved 38 TM patients and 25 healthy controls, revealing that SWE parameters were significantly higher in TM patients compared to healthy controls, indicating more advanced liver condition.
  • * Although no significant differences in SWE were found among TM patients with varying levels of iron overload, the study suggests that SWE could serve as a valuable tool for early liver damage detection, paving the way for further research.
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Article Synopsis
  • The study aimed to compare various clinical and hormonal characteristics, treatment methods, and survival outcomes of ectopic Cushing's syndrome (ECS) between male and female patients.
  • Data was collected from 11 medical centers, evaluating 54 patients (28 females and 26 males), and found similarities in age, clinical presentation, and hormone levels despite some differences like higher rates of diabetes and osteoporosis in males.
  • Overall, the results showed comparable disease progression, treatment responses, and remission rates between sexes, but indicated that males experience more severe conditions such as hyperglycemia and osteoporosis.
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Objective: Round shape is generally considered to reduce the risk of malignancy according to recent guidelines. On the contrary, according to some reports, spherically shaped thyroid nodules are associated with a higher risk of malignancy. Thus, we aimed to evaluate the malignancy risk of solid round isoechoic nodules detected at thyroid ultrasonography and compare it with that of solid ovoid isoechoic nodules.

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Background: Multiple endocrine neoplasia type 2B (MEN 2B) is a rare hereditary syndrome caused mainly by Met918Thr germline RET mutation and characterized by medullary thyroid carcinoma (MTC), pheochromocytoma (PHEO), and typical phenotypic features. MEN 2B cases previously reported in the literature have variable clinical course.

Objectives: We aimed to discuss the characteristics of four MEN 2B cases with unusual presentations,clinical course and review the recent clinical data on MEN2B.

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