Publications by authors named "A Giordani"

Myocarditis is an inflammatory disease of the myocardium with heterogeneous etiology, clinical presentation, and prognosis; when it is associated with myocardial dysfunction, this identifies the entity of inflammatory cardiomyopathy. In the last few decades, the relevance of the immune system in myocarditis onset and progression has become evident, thus having crucial clinical relevance in terms of treatment and prognostic stratification. In fact, the advances in cardiac immunology have led to a better characterization of the cellular subtypes involved in the pathogenesis of inflammatory cardiomyopathy, whether the etiology is infectious or autoimmune/immune-mediated.

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. Pericarditis has a heterogeneous clinical spectrum and rate of relapse. Data on aetiology, real-life treatment strategies, and long-term course from contemporary pericarditis cohorts are lacking.

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Article Synopsis
  • Autoantibodies against Desmoglein-2 (anti-DSG2-ab) were found in patients with Arrhythmogenic Right Ventricular Cardiomyopathy (ARVC) and myocarditis, indicating a potential link to immune responses against desmosomal proteins.
  • The study aimed to evaluate the specificity of anti-DSG2-ab in ARVC, compare detection methods (ELISA vs. IFL), and identify clinical correlates related to these antibodies among various patient groups.
  • In a cohort of patients, 56% of those with ARVC tested positive for anti-DSG2-ab, showing a higher rate of positivity in those also positive for anti-intercalated disk autoantibodies (A
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Article Synopsis
  • * Adsorption was the main PCP removal mechanism, showing high efficiency (86-104%) at various concentrations, while biodegradation produced toxic intermediates, with significant bacterial community impacts noted.
  • * Indigenous inoculum from the Santos-São Vicente estuary and polyurethane foam were effective in enhancing both the adsorption process and the overall PCP removal, without inhibiting microbial activity.
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Athletes with heart disease are at increased risk of malignant ventricular arrhythmias and sudden cardiac death compared to their sedentary counterparts. When athletes have symptoms or abnormal findings at preparticipation screenings, a precise diagnosis by differentiating physiological features of the athlete's heart from pathological signs of cardiac disease is as important as it is challenging. While traditional imaging methods such as echocardiography, cardiac magnetic resonance, and computed tomography are commonly employed, nuclear medicine offers unique advantages, especially in scenarios requiring stress-based functional evaluation.

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