Publications by authors named "A Gimpel"

Article Synopsis
  • The study aimed to examine how long-term use of calcineurin inhibitor (CNI)-based immunosuppressive drugs affects the structure of the rat jejunum and the balance of MMP-2 and its inhibitor TIMP-2.
  • Twenty-four rats were divided into four groups, each receiving different immunosuppressive treatments for six months, after which their jejunums were analyzed.
  • The results showed that these drugs negatively impacted the small intestine's morphology and disrupted the MMP-2/TIMP-2 balance, with tacrolimus causing the most significant changes, highlighting the need for further research and the potential of AI in analyzing tissue samples.
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Physical unclonable functions (PUFs) based on unique tokens generated by random manufacturing processes have been proposed as an alternative to mathematical one-way algorithms. However, these tokens are not distributable, which is a disadvantage for decentralized applications. Finding unclonable, yet distributable functions would help bridge this gap and expand the applications of object-bound cryptography.

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Archiving data in synthetic DNA offers unprecedented storage density and longevity. Handling and storage introduce errors and biases into DNA-based storage systems, necessitating the use of Error Correction Coding (ECC) which comes at the cost of added redundancy. However, insufficient data on these errors and biases, as well as a lack of modeling tools, limit data-driven ECC development and experimental design.

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Renal transplantation is now the best treatment for end-stage renal failure. To avoid rejection and prolong graft function, organ recipients need immunosuppressive therapy. The immunosuppressive drugs used depends on many factors, including time since transplantation (induction or maintenance), aetiology of the disease, and/or condition of the graft.

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Evaluating the ecological effects of the rapid expansion of offshore renewables at local, regional and ecosystem-wide scales is essential to understand the overall socio-ecological trade-offs also for other sectors such as fisheries. Hence, little is known about the ecological impact on demersal fish. To shed light on this topic, we studied the effects of an offshore wind farm in the southern North Sea on different life stages of Atlantic cod (Gadus morhua) using a combination of sampling methods at varying spatial and temporal scales.

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