Publications by authors named "A Gilioli"
Objective: We investigated the performance of enzyme linked immunospot (ELISpot) assay for the diagnosis of invasive aspergillosis (IA) in high-risk patients with hematologic malignancies.
Methods: We prospectively enrolled two cohorts of patients undergoing intensive myelosuppressive or immunosuppressive treatments at high risk for IA. ELISpot was performed to detect Aspergillus-specific T cells producing Interleukin-10.
Severe acute respiratory syndrome coronavirus 2 infection in patients with hematological malignancies in the Omicron era: Respiratory failure, need for mechanical ventilation and mortality in seronegative and seropositive patients.
Erica Franceschini Valentina Menozzi Vera Todisco Mariachiara Pellegrino Samuele Cantergiani Andrea Gilioli
EJHaem
June 2024
Article Synopsis
- Patients with hematological malignancies are at a higher risk for severe COVID-19 during the Omicron variant's prevalence, with significant health impacts observed in those with negative SARS-CoV2 serology.
- A study of 112 patients revealed that seronegative individuals were older, more likely to have certain types of cancer, and faced worse health outcomes, including higher rates of respiratory failure, mechanical ventilation, and COVID-related death.
- The findings suggest that negative SARS-CoV2 serology can serve as a useful indicator to identify patients at increased risk for severe complications from COVID-19, highlighting the importance of serology testing in managing these patients.
Article Synopsis
- This study examined the effectiveness of early palliative care (EPC) for patients with multiple myeloma (MM) compared to usual hematological care (UHC).
- Patients receiving EPC demonstrated significantly better quality indicators of care, such as pain management and advance care planning, indicating improved overall support.
- Despite the enhanced care quality with EPC, patient survival rates remained similar to those receiving UHC, underscoring the potential for EPC to improve the end-of-life experience without affecting longevity.
Introduction: Pain plays a fundamental role in the well-being of the individual, and its semantic content may have specific properties compared to other negative domains (i.e., fear and anger) which allows the cognitive system to detect it with priority.
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