Publications by authors named "A Ghanadan"
This study identifies microRNAs (miRNAs) with significant discriminatory power in distinguishing melanoma from nevus, notably hsa-miR-26a and hsa-miR-211, which have exhibited diagnostic potential with accuracy of 81% and 78% respectively. To enhance diagnostic accuracy, we integrated miRNAs into various machine-learning (ML) models. Incorporating miRNAs with AUC scores above 0.
View Article and Find Full Text PDFRepresentative clinical images in this study can increase awareness regarding the clinical similarity between this benign adnexal tumor and malignant melanoma and highlight the importance of pathological examination.
View Article and Find Full Text PDFArticle Synopsis
- Blastic plasmacytoid dendritic cell neoplasm (BPDCN) is a rare and aggressive form of blood cancer that poses diagnostic challenges for both clinicians and pathologists.
- A case study of a 71-year-old man with an ulcerated skin lesion illustrates key histopathological features, including atypical cells that test positive for specific markers, confirming BPDCN.
- The condition often presents with skin involvement characterized by purplish nodules and requires differentiation from similar conditions, emphasizing the need for pathologists to be aware of this rare malignancy for prompt diagnosis.
Background: Skin aging as a continuous and irreversible process is mainly the result of alterations of function and structure of the dermis. Among the modalities used for treating skin aging, carboxytherapy has been introduced as a safe minimally-invasive method for rejuvenation, reparation, and reconditioning of the skin.
Objective: We assessed the efficacy of carboxytherapy for the treatment of intrinsic skin aging through pathological and immunohistochemical (IHC) investigations.
Article Synopsis
- Pyogenic granuloma is a rapidly growing, red skin or mucosal lesion often seen in patients, which can bleed easily due to ulceration and is reported to be associated with COVID-19.
- A 52-year-old woman developed skin eruptions three weeks after her second COVID-19 vaccine dose.
- This case is noteworthy as it's the first documented instance of eruptive pyogenic granuloma following vaccination, and treatment with oral propranolol and PDL laser therapy showed effective results within six weeks.