Publications by authors named "A Ghalyanchilangeroudi"
Infectious bronchitis virus (IBV) has a variety of serotypes that cause many problems in the poultry industry. Two H120 and H120-D274 live vaccines were evaluated against strain IS/1494/06 (variant 2) IBV challenge. The study aimed to determine whether it was possible to achieve success in controlling disease symptoms and pathological lesions and reducing virus shedding by combining two types of vaccines against different severities of poultry IBV.
View Article and Find Full Text PDFArticle Synopsis
- Foot-and-mouth disease (FMD) poses major economic challenges to livestock globally, leading to a study in Iran that analyzed 90 samples from vaccinated cattle across 40 farms.
- Results showed a high prevalence of FMD, with 66.66% of samples testing positive, primarily identifying serotypes O, A, and Asia-1.
- The findings underscore the effectiveness of vaccination efforts in Iran but highlight the need for ongoing surveillance due to the persistence of these virus serotypes in different provinces.
Marek's disease is a significant illness in chickens and a potential threat to the poultry industry worldwide. Marek's disease virus (MDV) causes immunosuppression and lymphoproliferative disease in chickens, but the turkey is an unusual host for the virus, and tumors caused by MDV in turkeys are unique. This study sampled 15 asymptomatic commercial turkey flocks (five spleens from each flock) at slaughter.
View Article and Find Full Text PDFArticle Synopsis
- Crimean-Congo hemorrhagic fever (CCHF) is a serious viral disease transmitted mainly through tick bites, leading to severe hemorrhagic symptoms and has been found in Africa, Asia, and Europe.
- There is currently no widely approved vaccine or effective treatment for CCHF, although Ribavirin has been used in some regions with questionable efficacy results.
- Various innovative vaccine development strategies, including inactivated viruses and advanced DNA and mRNA approaches, are being explored and reviewed in ongoing research.
Article Synopsis
- CRISPR-Cas systems, originally used by bacteria for immunity, are being adapted to target and combat diseases caused by RNA viruses in plants and mammals.
- Researchers focused on Cas13 orthologs to effectively knockdown the foot-and-mouth disease virus (FMDV), which impacts many species worldwide due to its genetic diversity.
- The study found that various Cas13 enzymes could successfully suppress FMDV by targeting highly conserved regions of its genome, demonstrating a promising strategy for addressing other RNA viruses in animal health.