Publications by authors named "A Gambelunghe"

Article Synopsis
  • The mental well-being of healthcare professionals can be significantly harmed by unfavorable workplace conditions, leading to burnout and psychiatric issues, prompting the establishment of a psychological support service at the General Hospital of Perugia, Italy.
  • Launched in June 2022, this anonymous service aims to promote worker well-being, provide psychological support, and guide professionals towards appropriate care pathways.
  • From June 2022 to April 2024, the service had 139 visits, predominantly from women (80%) and nursing staff (53%), confirming high levels of work-related stress and highlighting the importance of early identification and stigma reduction in workplace mental health.
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Introduction: The increase in average air temperature and multiple extreme weather events, such as heatwaves and droughts, pose significant health risks to humans. This scoping review aims to examine the current state of the existing literature concerning the potential relationship between substance abuse and climate change, along with the aspects it encompasses.

Material And Methods: The review followed PRISMA guidelines for methodological rigor, aiming to identify studies on drug abuse.

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As time passes, the long-term effects of the COVID-19 pandemic are becoming increasingly apparent. The extreme restrictions imposed during the pandemic have had detrimental impacts on the most vulnerable groups, such as individuals suffering from substance and/or alcohol disorders (SUDs). This study reports quarterly laboratory data on alcohol and drug use in 150 subjects with SUDs that were examined using hair analysis for 2 years before the start of pandemic until after the end of the Italian health emergency.

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Lately, nickel oxide nanoparticles (NiO NPs) have been employed in different industrial and biomedical fields. Several studies have reported that NiO NPs may affect the development of reproductive organs inducing oxidative stress and, resulting in male infertility. We investigated the effects of NiO NPs on porcine pre-pubertal Sertoli cells (SCs) which undergone acute (24 h) and chronic (from 1 up to 3 weeks) exposure at two subtoxic doses of NiO NPs of 1 μg/ml and 5 μg/ml.

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Cigarette smoke (CS) represents one of the most relevant environmental risk factors for several chronic pathologies. Tissue damage caused by CS exposure is mediated, at least in part, by oxidative stress induced by its toxic and pro-oxidant components. Evidence demonstrates that extracellular vesicles (EVs) released by various cell types exposed to CS extract (CSE) are characterized by altered biochemical cargo and gained pathological properties.

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