Publications by authors named "A Galor"
Chronic ocular surface pain (COSP) refers to interrelated symptoms such as eye burning, aching, and irritation and can occur as an isolated condition or comorbid with numerous ocular disorders, including dry eye syndrome Treatments for COSP are largely aimed at the ocular surface and modulating pain arising from damaged corneal nerves; however, the average impact of these treatments on COSP are low to absent. A potential explanation for this is that in a subset of patients with COSP, individuals have amplified and/or dysregulated neural signaling and sensory processing within the central nervous system (CNS). As in other chronic pain conditions, this might be the pathogenic mechanism primarily responsible for maintaining pain - a phenomenon now referred to as nociplastic pain.
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- The gut microbiome's influence on eye health is a growing area of research, particularly how imbalances in gut bacteria can lead to eye diseases like dry eye, uveitis, and glaucoma.
- Dysbiosis in the gut is associated with immune system issues, chronic inflammation, and problems with the eye's protective layers, which can worsen eye health.
- The review discusses potential treatments targeting the gut microbiome, such as antibiotics, prebiotics, probiotics, and fecal transplants, that could help rebalance gut bacteria and improve immune responses to better manage eye diseases.
Purpose: Friedreich ataxia (FDRA) is a debilitating neurodegenerative disease that can have ophthalmological manifestations including visual dysfunction, nystagmus, and optic atrophy. However, severe photophobia has not been reported nor evaluated with functional magnetic resonance imaging (fMRI).
Methods: A 64-year-old white female with a 37-year history of FDRA presented to the eye clinic with worsening photophobia of 3 years.