Analysis of the Effectiveness of Coordinated Care in the Management of Pharmacotherapy of Patients with Hypertension and Comorbidities in Primary Care-Preliminary Reports.

Hypertension (HTN) is the dominant cause of cardiovascular disease and premature death worldwide. Also in Poland, the number of people with HTN is steadily increasing. In order to improve care for patients with HTN and other chronic diseases, a pilot of the POZ PLUS coordinated-care model was introduced.

FET fusion oncoproteins disrupt physiologic DNA repair networks in cancer.

While oncogenes promote cancer cell growth, unrestrained proliferation represents a significant stressor to cellular homeostasis networks such as the DNA damage response (DDR). To enable oncogene tolerance, many cancers disable tumor suppressive DDR signaling through genetic loss of DDR pathways and downstream effectors (e.g.

Comparative analysis of physical, morphological, and mechanical characteristics of eggs from three pheasant subspecies.

The profitability of pheasants breeding is influenced by many factors, but eggs quality is considered as the backbone for successful pheasant breeding. The objective of this study was to determine and compare various quality characteristics (physical, morphological, and mechanical) of eggs from three pheasant subspecies: common pheasant (Phasianus colchicus colchicus), Mongolian pheasant (Phasianus colchicus mongolicus), and black pheasant (Phasianus colchicus vs. tenebrosus).

Plant Response to Mechanically-Induced Stress: A Case Study on Specialized Metabolites of Leafy Vegetables.

Plants have evolved various adaptive mechanisms to environmental stresses, such as sensory mechanisms to detect mechanical stimuli. This plant adaptation has been successfully used in the production practice of leafy vegetables, called mechanical conditioning, for many years, but there is still a lack of research on the effects of mechanically-induced stress on the content of specialized metabolites, or phytochemicals with significant antioxidant activity. Therefore, the aim of this study was to determine the content of specialized metabolites and antioxidant capacity of lettuce and green chicory under the influence of mechanical stimulation by brushing.

Ultrasound as a Promising Tool for the Green Extraction of Specialized Metabolites from Some Culinary Spices.

Spices are a popular food of plant origin, rich in various phytochemicals and recognized for their numerous properties. The aim of the study was to evaluate the antioxidant and antimicrobial activity, as well as the content of specialized metabolites, of aqueous extracts of three spice species--garlic ( L.), ginger ( L.