Publications by authors named "A Galan-Brotons"
Purpose: Trastuzumab has proven to improve the prognosis of HER2-positive breast cancer, but the information available about its administration for small tumors is still limited. Therefore, we assessed the use of adjuvant regimens with trastuzumab for the treatment of small HER2-positive breast cancer in routine clinical practice.
Methods: This observational study was conducted in patients with HER2-positive breast adenocarcinoma ≤1.
We conducted a multicentre, retrospective, observational study including patients with solid tumours (excluding breast cancer) that received granulocyte colony-stimulating factors (G-CSF) and chemotherapy. We investigated the effectiveness of daily vs. non-daily G-CSFs (pegfilgrastim) adjusting by potential confounders.
View Article and Find Full Text PDFA woman diagnosed of a renal cell carcinoma in 1989 had a metastatic kidney cancer localised in subcutaneous nodules, gut and lung in 2007. Sorafenib treatment was initiated a 400 mg orally twice a day. The patient developed generalised erythematous skin eruptions and two weeks later a widespread erythematous maculopapular eruption located exclusively on the legs and arms, along with an objective response.
View Article and Find Full Text PDFSuccessful desensitization protocol for hypersensitivity reactions caused by oxaliplatin.
Int J Clin Pharmacol Ther
November 2007
Objective: To report the successful desensitization of a patient with a hypersensitivity reaction to oxaliplatin.
Case Summary: A 57-year-old woman with metastatic colon cancer was receiving oxaliplatin, fluorouracil and leucovorin every 2 weeks and showed a partial response to therapy. During the fourth cycle, an anaphylactic reaction with palpitations and rash occurred.