Publications by authors named "A G Zauber"

Background & Aims: Whether gastric cancer (GC) precursor lesions progress to invasive cancer at similar rates globally remains unknown. We conducted a systematic review and meta-analysis to determine the progression of precursor lesions to GC in countries with low versus medium/high incidence.

Methods: We searched relevant databases for studies reporting the progression of endoscopically confirmed precursor lesions to GC.

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Article Synopsis
  • The Affordable Care Act removed out-of-pocket costs for recommended preventive services, but a recent court ruling may reinstate these costs for over 150 million Americans, particularly affecting colorectal cancer screenings.
  • If the court's decision stands, it could specifically impact screening for colorectal cancer in people aged 45-49 and polyp removals during colonoscopies for all ages.
  • A simulation showed that a decrease in screening participation by 8% could lead to a significant rise in colorectal cancer cases and deaths, while potentially reducing costs in the short term due to increased cost-sharing, but higher participation loss could result in greater overall healthcare costs.
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Importance: The fecal immunochemical test (FIT) is widely used for colorectal cancer (CRC) screening, but evidence of its effectiveness is limited.

Objective: To evaluate whether FIT screening is associated with a lower risk of dying from CRC overall, according to cancer location, and within demographic groups.

Design, Setting, And Participants: This nested case-control study in a cohort of screening-eligible people was conducted in 2 large, integrated health systems of racially, ethnically, and socioeconomically diverse members with long-term programs of mailed FIT screening outreach.

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