Background: Lesion size is an independent risk factor for recurrence following endoscopic mucosal resection of large (≥20 mm) non-pedunculated colorectal polyps. Post-resection margin thermal ablation (MTA) reduces the risk of recurrence. Its impact on the uncommon larger (≥40 mm) lesions is unknown.
View Article and Find Full Text PDFBackground And Study Aims: Non-lifting large non-pedunculated colorectal polyps (NL-LNPCPs) account for 15% of LNPCP and are effectively managed by Endoscopic Mucosal Resection with adjunctive Cold-forceps Avulsion with adjuvant Snare-Tip soft coagulation (CAST). However, recurrence rates > 10% at surveillance colonoscopy is a significant limitation. We aimed to compare the outcomes of CAST with MTA versus CAST alone for NL-LNPCPs.
View Article and Find Full Text PDFRuvbl1 (also known as TIP49, Pontin) encodes an ATPase of the AAA+ protein superfamily involved in several cellular functions, including chromatin remodeling, control of transcription, and cellular development (motility, growth, and proliferation). While its role has been well established in model organisms including vertebrates and invertebrates (e.g.
View Article and Find Full Text PDFTomato spotted wilt virus (TSWV) is transmitted by insect pests from the Thripidae family, including Frankliniella occidentalis, commonly known as western flower thrips. For experimental purposes, researchers have developed methods for inoculating host plants with TSWV, allowing thrips to acquire TSWV, and verifying thrips acquisition. Plants can be inoculated with TSWV either mechanically or with thrips in the lab, but in nature, the virus is transmitted by thrips.
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