Publications by authors named "A G Vasilyeva"

Article Synopsis
  • This study aimed to determine the relative biological effectiveness (RBE) of carbon ion beams in particle radiotherapy, focusing on different regions of the Bragg curve while comparing it to X-ray radiation.
  • SHK mice were irradiated at varying doses (0-1.5 Gy for cytogenetic damage and 6.5 Gy for survival) to assess the effects of carbon ions in the Bragg peak using different widths of the spread-out Bragg peak (SOBP).
  • Results indicated that RBE values were lower before and after the Bragg peak (0.8-0.9), but increased significantly in the low-dose region (1.1-1.7 for 10-mm SOBP), suggesting
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Phytopathogenic bacteria of the genus are responsible for several diseases that affect potato ( L.) production worldwide, including blackleg and tuber soft rot. These bacteria are highly diverse, with over 17 different species currently identified.

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The article demonstrates a detailed analysis of the results of the rounds of quality control of immunohistochemical studies conducted by the Central Committee of the Immunohistochemical Quality Control Center of the Russian Medical Academy of Continuous Professional Education of the Ministry of Health of Russia in 2023. Typical shortcomings and errors in the immunohistochemical examination of various tumors have been identified and ways to eliminate them are given. Particular attention is paid to defining a panel of standard breast cancer markers and eliminating the shortcomings of immunohistochemical examination of markers of accompanying diagnosis.

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Immune system and bone marrow stromal cells play an important role in maintaining normal hematopoiesis. Lymphoid neoplasia disturbs not only development of immune cells, but other immune response mechanisms as well. Multipotent mesenchymal stromal cells (MSCs) of the bone marrow are involved in immune response regulation through both intercellular interactions and secretion of various cytokines.

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Reactive oxygen species (ROS) are constantly generated in a living organism. An imbalance between the amount of generated reactive species in the body and their destruction leads to the development of oxidative stress. Proteins are extremely vulnerable targets for ROS molecules, which can cause oxidative modifications of amino acid residues, thus altering structure and function of intra- and extracellular proteins.

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