[Induced contractile activity of smooth muscles of the large intestine in rats after NO-syntase inhibition].

NO involvment in the mechanisms of the contractile activity of the smooth muscle cells was studied in the colon. The differences in the effects of different transmitters on the kinetics of the contractile activity after NOS inhibition have been determined.

[Daily rhythms of cortisol and serotonin concentrations in children with chronic viral hepatitis].

The daily rhythms of cortisol (C) and serotonin (S) concentrations were investigated in saliva of children with chronic viral hepatitis HBV and HCV. The changes in chronostructure of C and S rhythms were revealed to depend on the viral type and an intensity of the liver inflammatory process. The circadian rhythms of C and S were found to be desynchronized which was manifested as quantitative (period) and qualitative (mesor value, amplitude of oscillations, daily acro- and miniphase) changes in the rhythm.

[Efficiency of enterosorbents and detoxication mechanisms in immature rats with simulated hepatitis].

Different modifications of fibrous enterosorbent of the ACFM "Dnepr-MN" type exert a normalizing effect on the morphofunctional state of the liver of preadolescent rats with the model of toxic hepatitis. The distortion in the oxidation of lipids with peroxide and in the antioxidizing system protection removed, antitoxic liver function increases, which is confirmed by microsomal oxidation processes. A mediated effect of enterosorbents on the hepatocyte membrane structures is very significant for their detoxication effect.