Publications by authors named "A G T Cozma"
Feline Panleukopenia (FPL) infection is caused by feline panleukopenia virus (FPV), and it is considered one of the most severe cat's infectious diseases. Since there is no specific antiviral treatment for FPL, the therapeutic protocol usually is focused on fluid therapy and supportive care. However, filgrastim, a granulocyte colony-stimulating factor (G-CSF) used in human medicine to treat neutropenia and leukopenia, has been lately used in treating FPV disease, providing promising results.
View Article and Find Full Text PDFAdvancements in radiotherapy technology now enable the delivery of ablative doses to targets in the upper urinary tract, including primary renal cell carcinoma (RCC) or upper tract urothelial carcinomas (UTUC), and secondary involvement by other histologies. Magnetic resonance imaging-guided linear accelerators (MR-Linacs) have shown promise to further improve the precision and adaptability of stereotactic body radiotherapy (SBRT). This single-institution retrospective study analyzed 34 patients (31 with upper urinary tract non-metastatic primaries [RCC or UTUC] and 3 with metastases of non-genitourinary histology) who received SBRT from August 2020 through September 2024 using a 1.
View Article and Find Full Text PDF: Heart failure (HF) is one of the most common initial presentations of cardiovascular disease (CVD) in patients with type 2 diabetes mellitus (T2DM). There are different cardiac biomarkers related to the pathophysiological mechanisms of HF in T2DM. The current research aims to identify additional biomarkers that could improve the diagnosis and prognosis of HFpEF, which is currently assessed using NT pro-BNP levels.
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- * The study examined the relationship between certain gene variations (polymorphisms) of IL17 and TLR4 and their impact on the likelihood of developing metabolic associated fatty liver disease (MASLD), using genetic testing and serum level analysis.
- * Findings revealed that individuals with specific genetic variants of IL17 and TLR4 had significantly higher odds of developing conditions like metabolic associated steatotic liver disease (MASH) and metabolic associated fatty liver (MAFL); notably, certain alleles were strongly correlated with these increased risks.
Article Synopsis
- Type 2 diabetes mellitus (T2DM) is a growing metabolic disorder that often leads to diabetic cardiomyopathy (DCM), a severe condition contributing to high mortality rates among diabetic patients.
- Early stages of DCM show no symptoms and have normal heart function, making it hard to detect, and current clinical markers lack specificity for early diagnosis.
- This review highlights the need for new biomarkers for early DCM diagnosis, discussing promising candidates like galectin-3 and ST2, to improve recognition and treatment outcomes.