Publications by authors named "A G Samarina"
We evaluated the effectiveness and safety of direct-acting antivirals in adolescents with hepatitis C (HCV)/HIV coinfection using pooled individual patient-level data from 5 European cohorts. Of 122 participants in follow-up from November 2013 to August 2021, 19 were treated <18 years of age; of 15 with HCV RNA available at/after 12 weeks post-treatment, all had sustained virologic response with acceptable safety. This evidence addresses an important gap in knowledge of treatment outcomes in adolescents with HCV/HIV coinfection in real-life settings.
View Article and Find Full Text PDFA high-density single nucleotide polymorphism (SNP) array is essential to enable faster progress in plant breeding for new cultivar development. In this regard, we have developed an Axiom 60K almond SNP array by resequencing 81 almond accessions. For the validation of the array, a set of 210 accessions were genotyped and 82.
View Article and Find Full Text PDFOutcomes of etravirine-based antiretroviral treatment in treatment-experienced children and adolescents living with HIV in Europe and Thailand.
Antivir Ther
June 2022
Article Synopsis
- Etravirine (ETR) is used for second or third-line antiretroviral treatment in children with HIV, and a study assessed its outcomes in children across Europe and Thailand.
- Data was collected from 177 children, showing that 69% achieved viral suppression after 12 months and experienced an increase in CD4 cell counts; however, 46% discontinued ETR due to reasons such as treatment simplification and failure.
- Some adverse events were reported, including rare but serious reactions like Stevens-Johnson Syndrome, but overall, ETR proved effective for many treatment-experienced children.
Background: Earlier studies have demonstrated a high prevalence of atrial fibrillation (AF) in patients with CHF. It was noticed that tachycardia and hypotension provoked high risks for cardiovascular mortality. The presence of arterial hypertension (AH) in CHF patients also impairs life prognosis.
View Article and Find Full Text PDFGenerally, women are less likely than men to disclose their HIV status. This analysis examined the relationship between HIV disclosure and (1) perceived barriers to care and (2) quality of life (QoL) for women with HIV. The ELLA (EpidemioLogical study to investigate the popuLation and disease characteristics, barriers to care, and quAlity of life for women living with HIV) study enrolled HIV-positive women aged ≥18 years.
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