Continuous quality improvement for prehospital STEMI improved triage rates and achievement of gold standard < 90-min EMS-to-balloon time.

Background: ST-elevation myocardial infarction (STEMI) is a type of myocardial infarction caused by a buildup of plaque or clot in the coronary arteries. There are approximately 750,000 STEMI cases each year in the United States. The American Heart Association's Mission Lifeline initiative aimed to optimize prehospital emergency medical services (EMS) and enhance STEMI triage rates through improved standardized protocol.

Characterization of the procoagulant phenotype of amniotic fluid across gestation in rhesus macaques and humans.

Background: Amniotic fluid (AF) plays a key role in fetal development, yet the evolving composition of AF and its effects on hemostasis and thrombosis are poorly understood.

Objectives: To characterize the procoagulant properties of AF as a function of gestation in humans and nonhuman primates.

Methods: We analyzed the proteomes, lipidomes, and procoagulant properties of AF obtained by amniocentesis from rhesus macaque and human pregnancies at gestational age-matched time points.

Low-cost and automated magnetic bead-based DNA data writing digital microfluidics.

The rapid growth in data generation presents a significant challenge for conventional storage technologies. DNA storage has emerged as a promising solution, offering substantially greater storage density and durability. However, the current DNA data writing process is costly and labor-intensive, hindering the commercialization of DNA data storage.

Changes in primary care encounter rates during the veteran health administration's electronic health record transition.

Background: Electronic health record (EHR) transitions can cause major disruptions in the provision of primary care services. Veteran Health Administration (VHA), one of the largest integrated healthcare systems, underwent a major EHR transition at two sites. To date, there is limited data on the experience of primary care service lines at EHR transition sites.