Exploring factors required for successful implementation of healthcare informatics.

This paper examines factors that are essential for a successful implementation of healthcare informatics in professional curricula. These factors are related to the design framework of the learning materials that have been developed as a part of a Dutch model curriculum of healthcare informatics. Next some ideas and suggestions for a successful implementation are presented.

Production of pheromone by hairpencil glands of males obtained from interspecific hybridization betweenHeliothis virescens andH. subflexa (Lepidoptera: Noctuidae).

Pheromone produced by the hairpencil glands of interspecific hybrid- and backcross-generation males from crosses betweenHeliothis virescens (F.) withH. subflexa (Gn.

Sex difference in Aroclor 1254 induction of rat hepatocytes: Consequences for in vitro embryotoxicity and mutagenicity of cyclophosphamide.

The sequential culture of rat hepatocytes and post-implantation rat embryos has been proposed as a model for the in vitro testing of pro-teratogens. Comparing this model with a model in which embryos and hepatocytes are cultured simultaneously a striking difference in sensitivity was noted. To address the question of whether this difference could be explained by different sex and/or Aroclor 1254 pretreatment of the rats providing the hepatocytes, an experiment was designed with four groups: male Aroclor 1254 pretreated (M(1)), male untreated, pregnant female Aroclor 1254 pretreated (F(1)) and pregnant female untreated rats.

An apparently new syndrome of microcephalic primordial dwarfism and cataracts.

We describe two sibs with prenatal-onset growth deficiency, microcephaly, cataracts, mental retardation, enamel hypoplasia, immune deficiency, and generalized delay of ossification. The combination appears to constitute a previously undescribed autosomal recessive syndrome.