[Diagnostic and prognostic value of quantitative indicators of 12 ECG leads in ischemic heart disease].

The study was undertaken to examine 35 patients with chronic coronary heart disease and 20 patients with neurocirculatory dystonia concurrent with the cardialgic syndrome, the latter were enrolled into a control group. Detection of sigma R in the standard leads of resting ECG and at the peak of atrial pacing made it possible to single out groups of chronic coronary heart disease patients, which differed in clinical manifestations of the disease, myocardial contractility, hemodynamics, and myocardial lactate extraction. In patients with chronic coronary heart disease ti is recommended to use ECG measurements (sigma R and nST) in the standard leads during loading tests to give a comprehensive characterization of the pump function and the severity of myocardial ischemia, the prognosis of the natural history of the disease and risk for myocardial infarction.

[Relation between indices of ECG cartography, central hemodynamics and myocardial energy metabolism in acute infarct].

A study of 30 patients with acute myocardial infarction, including the assessment of central hemodynamic parameters, ECG records from 35 leads and the investigation of myocardial energy metabolism by means of lactate, nonesterified fatty acids and glucose measurement in coronary venous blood, demonstrated that hyperkinetic hemodynamics was associated with a great spread of the necrotic and ischemic zone and predominant myocardial extraction of nonesterified fatty acids in uncomplicated acute myocardial infarction. It is suggested that propranolol should be used in those cases where hyperkinetic hemodynamics complicate the course of acute myocardial infarction.

[Comparison of the indices of left ventricular pumping function, contractility, myocardial metabolism and the magnitude of the R wave on the ECG of ischemic heart disease patients].

Central hemodynamics, myocardial contractility and consumption of major energy substrates (lactate, glucose, non-esterified fatty acids, NEFA), as well as the total R wave amplitude from 12 standard leads were assessed in 20 patients with neurocirculatory dystonia (the control group) and 36 patients with chronic coronary disease. The changes in central hemodynamics and contractility were particularly marked in 12 of the more severe coronary cases with a raised total R wave amplitude. Myocardial energy supply in such patients is provided at the expense of NEFA.