With the aim of exploring the source of the high variability observed in the production of perezone, in wild plants, we analyze the influence of soil parameters and phenotypic characteristics on its perezone content. Perezone is a sesquiterpene quinone responsible for several pharmacological effects and the . plants are the natural source of this metabolite.
View Article and Find Full Text PDFMethyl parathion is an organophosphorus pesticide widely employed worldwide to control pests in agricultural and domestic environments. However, due to its intensive use, high toxicity, and environmental persistence, methyl parathion is recognized as an important ecosystem and human health threat, causing severe environmental pollution events and numerous human poisoning and deaths each year. Therefore, identifying and characterizing microorganisms capable of fully degrading methyl parathion and its degradation metabolites is a crucial environmental task for the bioremediation of pesticide-polluted sites.
View Article and Find Full Text PDFThe CRISPR-Cas cluster is found in many prokaryotic genomes including those of the Enterobacteriaceae family. serovar Typhi (. Typhi) harbors a Type I-E CRISPR-Cas locus composed of , , , , , , , , and a CRISPR1 array.
View Article and Find Full Text PDFOncol Rep
August 2020
Glioblastoma is a difficult disease to diagnose. Proteomic techniques are commonly applied in biomedical research, and can be useful for early detection, making an accurate diagnosis and reducing mortality. The relevance of mitochondria in brain development and function is well known; therefore, mitochondria may influence the development of glioblastoma.
View Article and Find Full Text PDFLtrR is a LysR-type regulator involved in the positive expression of to promote and expression. This regulatory network is fundamental for the control of bacterial transformation and resistance to the bile salt sodium deoxycholate in serovar Typhi. In this work, the transcriptional regulation of was characterized, revealing that the use of alternative promoters results in two transcripts.
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