[Morpho-biophysical research of erythrocytes of intact and vagotomized rats in various terms after the acute hemorrhage].

The acute massive hemorrhage (35-37% of the blood volume) at rats is accompanied by changes of morphological (diameter, the area, polarizations, the form-factor, integrated and specific absorbency) and biophysical (a relief of a surface and microviscosity of a lipid phase of plasmolemma) characteristics of erythrocytes. Thus character and dynamics of response of erythron initially intact and vagotomized (14 days after operation) animals essentially differ: the former demonstrate significant changes in 3-10 h and 240 h and the latter--in 0.5 h and 96 h.

[Lipid-proteinic interaction in erythrocytie and placental membranes in women with insulin resistance].

Disturbances of erythrocyte and placental membrane functiond have been studied in placenta of pregnant women with obesity and diabetes mellitus type 2. The results of this study demonstrate significant metabolic impairments in women with insulin resistance. Changes in lipid spectrum of erythrocyte membranes and decreased activity of antioxidant enzymes obviously contribute to the development of fetoplacental insufficiency.

Relationships between erythrocyte membrane properties and components of metabolic syndrome in women.

Background: Membrane structure in metabolic syndrome has not been fully investigated. The aim of our study was to determine the relationship between structural parameters of the erythrocyte membrane and blood pressure, indices of obesity, plasma lipids, and glucose levels in female patients with metabolic syndrome.

Material/methods: In 23 women with metabolic syndrome and 12 control normotensive women, anthropometric indices, blood pressure, and serum lipids were evaluated and an oral glucose tolerance test was performed.

Lipid-protein complexes in erythrocyte membrane in late gestosis.

Gestosis is characterized by increased rigidity of the surface and deep layers of erythrocyte membranes, impaired protein-lipid relationships, and imbalance between LPO and the antioxidant defense system. These changes determine the prognosis and complications of this condition.

[Effect of insulin on lipid peroxidation in the erythrocyte membranes of patients with insulin dependent diabetes mellitus].

The spin-probe techniques has been used to study insulin-membranes interaction in erythrocytes by insulin dependent diabetes mellitus. The lipid peroxidation has been initiated by FeSO4-ascorbate. It was found the insulin defend the lipids in control by peroxidation, but no effect in insulin dependent diabetes mellitus erythrocytes.