Publications by authors named "A G Kurkchubasche"

Article Synopsis
  • The study aimed to find which surgical treatment for premature infants with necrotizing enterocolitis (NEC) or isolated intestinal perforation (IP) led to lower rates of death or neurodevelopmental impairment (NDI).
  • Researchers conducted a large trial with 310 infants across 20 US centers, comparing laparotomy and peritoneal drainage as initial treatments and assessing outcomes at 18 to 22 months.
  • Results showed similar rates of death or NDI overall (69% for laparotomy vs. 70% for drainage), but preoperative diagnosis influenced outcomes, with laparotomy being more beneficial for NEC but less for IP.
View Article and Find Full Text PDF

Objective: To expand existing statistical methods to identify clusters of necrotizing enterocolitis (NEC) and spontaneous intestinal perforation (SIP) cases in the neonatal intensive care unit.

Methods: In an academic, tertiary referral center, possible NEC or SIP clusters were identified using a binomial distribution scan test. The incidence-density rate (IDR) was calculated as the number of cases per 1,000 patient-days during each possible cluster and compared with the baseline IDR.

View Article and Find Full Text PDF

Guidelines for the management of Parkinson's disease (PD) patients in the perioperative setting are lacking. Areas covered: Here we review potential problems that may arise when PD patients are undergoing an operation. We also review the literature, where available, and provide our expert opinion and recommendations based on experience.

View Article and Find Full Text PDF

We report the case of an 11-year-old girl with Peutz-Jeghers syndrome and a unilateral ovarian tumor most consistent with Sertoli cell tumor associated with sex cord tumor with annular tubules. The ovary was replaced by a lobular, solid, yellow tumor. Microscopic examination showed 2 components that focally merged.

View Article and Find Full Text PDF