Publications by authors named "A G Kuchin"

Article Synopsis
  • * Mice received a single dose of dibornol at varying levels, while rats were given a lower dose before and after treatment with cytostatic drugs like methotrexate and doxorubicin.
  • * The results showed dibornol did not have a genotoxic effect and significantly decreased spontaneous DNA damage in the bone marrow, as well as reduced DNA breaks caused by the cytostatic drugs.
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The intermetallic compounds GdFeCrSi, = 0-0.8, GdFeVSi, = 0-0.4, and GdFeNiSi, = 0-0.

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This article is devoted to the development of new photostabilizers for polylactide (PLA), a polymer that is an environmentally friendly alternative to polymers and is based on fossil raw materials. We have elucidated the role of the reaction center of two potential PLA photoprotectors: -isobornylaniline and 2-isobornylphenol, in reactions occurring in a polymer matrix under the action of UV-C radiation. PLA samples with the photostabilizers were irradiated under a wavelength of 253.

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We studied the effect of antioxidants dibornol (2,6-diisobornyl-4-methylphenol) and its derivative (4-hydroxymethyl-2,6-diisobornylphenol), members of the alkylated phenols group, on the redox potential of male germ cells and their morphological and functional state in the rat model of pathospermia. Pharmacological effect was observed in animals treated with dibornol. The studied compounds led to the normalization of the antioxidant-prooxidant balance.

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The synthesis of new chiral copper(ii) complexes with terpene derivatives of ethylenediamine and the results of studying their antibacterial, antifungal and antioxidant activity are discussed. All studied copper complexes (1-4) showed significantly higher antifungal activity against the strains of , and compared to the activity of the clinical antifungal drug amphotericin. High antibacterial activity of copper complexes with terpene derivatives of ethylenediamine was revealed against the (MRSA) strain, which is resistant to the reference antibiotic ciprofloxacin.

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