Publications by authors named "A G Kidd"

Objective: The objective was to assess whether cholesterol concentration at admission was associated with outcome and disease severity in dogs with sepsis, and to determine whether there was a significant difference in cholesterol between dogs with gram-positive gram-negative sepsis.

Animals And Procedure: Electronic medical records of dogs diagnosed with sepsis at a tertiary teaching hospital from 2012 to 2022 were evaluated. A total of 299 dogs were included.

View Article and Find Full Text PDF

Chlamydiosis is a common infectious disease impacting koalas and is a major cause of population decline due to resulting mortality and infertility. Polymorphisms of major histocompatibility complex (MHC) genes influence chlamydial disease outcomes in several species but koala studies have produced variable results. We aimed to identify the MHC II DAB and DBB repertoire of koalas from Liverpool Plains, NSW, a population heavily impacted by chlamydiosis.

View Article and Find Full Text PDF

Introduction: Altered body composition is associated with adverse survival in multiple cancers. We determined the prevalence, prognostic significance and clinicopathological correlates of sarcopenia and adipopenia in Pleural Mesothelioma (PM) patients receiving chemotherapy.

Methods: We performed a multi-centre retrospective cohort study.

View Article and Find Full Text PDF
Article Synopsis
  • Targeting tumor cell metabolism has emerged as a promising cancer therapy approach, but the complex nature of cancer metabolism presents challenges in finding effective treatments.
  • We used advanced modeling techniques to analyze metabolic states across various cancer cell lines, revealing connections to tumor types and identifying vulnerabilities in different genetic and tissue contexts.
  • Our research highlights specific metabolic states linked to genetic mutations and potential treatment targets, which could lead to more precise and tailored cancer therapies.
View Article and Find Full Text PDF

Our skin is home to a diverse community of commensal microorganisms integral to cutaneous function. However, microbial dysbiosis and barrier perturbation increase the risk of local and systemic infection. Staphylococcus aureus is a particularly problematic bacterial pathogen, with high levels of antimicrobial resistance and direct association with poor healing outcome.

View Article and Find Full Text PDF