Zh Vopr Neirokhir Im N N Burdenko
June 2021
The authors report a patient with recurrent bifocal germinoma of the optical nerves and chiasm after previous combined treatment. The tumor resulted progressive visual acuity loss despite subsequent therapy (glucocorticoid therapy, chemo- and radiotherapy). Differential diagnosis between tumor progression and consequences of radiotherapy was complicated by MRI negative pattern.
View Article and Find Full Text PDFZh Vopr Neirokhir Im N N Burdenko
February 2021
Objective: The analyze the neuro-ophthalmic outcomes in patients with pineal and suprasellar germinoma after complex treatment.
Material And Methods: There were 125 patients (88 males, 37 females) with primary CNS germinoma for the period 2008-2017. All patients were divided into 3 groups depending on the tumor localization: pineal area - 62 patients, suprasellar neoplasm - 38 patients, bifocal germinoma - 25 patients.
Purpose: To analyze neuro-ophthalmology symptoms in patients with germinomas located in pineal and suprasellar regions.
Material And Methods: The study analyzed 133 patients with germinoma who were receiving treatment in Burdenko Neuro-surgical Institute from 2008 to 2017. Assessment of results was performed by neuro-ophthalmology examination, a computerized oculograph was used for the objectification of the severity of ocular-motor and pupillary disorders.