Estimating the impact of school closures on the COVID-19 dynamics in 74 countries: A modelling analysis.

Background: School closures have been a prominent component of the global Coronavirus Disease 2019 (COVID-19) response. However, their effect on viral transmission, COVID-19 mortality and health care system pressure remains incompletely understood, as traditional observational studies fall short in assessing such population-level impacts.

Methods And Findings: We used a mathematical model to simulate the COVID-19 epidemics of 74 countries, incorporating observed data from 2020 to 2022 and historical school closure timelines.

Contemporary management of phyllodes tumours of the breast: proposal for recommendations from the UK Association of Breast Surgery.

Phyllodes tumours of the breast are rare fibroepithelial neoplasms classified histologically into benign, borderline, or malignant; each requiring different treatment strategies. The infrequency of presentation can result in diagnostic and management variability. The aim is to provide evidence-based or expert consensus recommendations for multidisciplinary teams managing patients with phyllodes tumours.

The Sugar-Coated Truth: The Quality of Diabetes Health Information on TikTok.

This study aimed to assess diabetes health information found on TikTok and quantify misinformation on TikTok. The authors assessed 171 videos through two health literacy tools, DISCERN and the Patient Education Materials Assessment Tool for Audiovisual Materials, to rate the understandability and actionability of online medical content. The findings from this study encourage health care professionals to use social media platforms to provide factual information about diabetes and advise online health care consumers to use reputable sources such as trusted diabetes organizations' social media accounts, which tend to validate content with clinicians.

Comparison of Diabetes Education Content Experienced by Blind and Nonblind People With Diabetes.

This survey sought to examine disparities in diabetes self-management education and support (DSMES) to illuminate gaps underlying morbidity and mortality disparities experienced by blind people with diabetes and develop a pathway for improved health care delivery and health outcomes. Blind participants were more likely to report getting DSMES on strategies to promote treatment adherence and noncompliance with medical regimen; yet, blind and nonblind participants did not differ on primary care provider visits or amount of time spent in diabetes education. These findings suggest that DSMES content may differ for blind versus nonblind participants.

Programmed shape transformations in cell-laden granular composites.

Tissues form during development through mechanical compaction of their extracellular matrix (ECM) and shape morphing, processes that result in complex-shaped structures that contribute to tissue function. While observed in vivo, control over these processes in vitro to understand both tissue development and guide tissue formation has remained challenging. Here, we use combinations of mesenchymal stromal cell spheroids and hydrogel microparticles (microgels) with varied hydrolytic stability to fabricate programmable and dynamic granular composites that control compaction and tissue formation over time.