Colonic strictures in Crohn's disease: a non-surgical survival.

Background: Colonic stenosis in Crohn's disease (CD) is uncommon, and data on surgery-free survival are limited. This study aimed to determine surgery-free survival rates and identify associated factors.

Patients And Methods: A retrospective study was conducted from 2003 to 2022, including patients with CD complicated by colonic stenosis.

Focused ultrasound therapy as a strategy for improving glioma treatment.

The infiltrative and diffuse nature of gliomas makes complete resection unfeasible. Unfortunately, regions of brain parenchyma with residual, infiltrative tumor are protected by the blood-brain barrier (BBB), making systemic chemotherapies, small-molecule inhibitors, and immunotherapies of limited efficacy. Low-frequency focused ultrasound (FUS) in combination with intravascular microbubbles can be used to disrupt the BBB transiently and selectively within the tumor and peritumoral region.

Seismic refraction investigation of the shallow bedrock in New Qena City, Eastern Desert, Egypt.

The seismic refraction technique has demonstrated its efficiency as a cost-effective geophysical approach for bedrock investigation, which is very important for major construction projects. In the southern part of New Qena City, in the Eastern Desert of Egypt, construction of many domestic facilities is planned. Therefore, a prior investigation focusing on bedrock is required to validate the site for construction and other projects.

Non-linear enhancement of ultrafast X-ray diffraction through transient resonances.

Diffraction-before-destruction imaging with ultrashort X-ray pulses can visualize non-equilibrium processes, such as chemical reactions, with sub-femtosecond precision in the native environment. Here, a nanospecimen diffracts a single X-ray flash before it disintegrates. The sample structure can be reconstructed from the coherent diffraction image (CDI).