Two isoniazid-based chemosensors for the detection of cyanide ions in solution: an experimental and computational study.

Colorimetric chemosensors L and L, based on isoniazid hydrazones, have been designed for the highly sensitive and selective recognition of CN ion. Competing experiments were conducted with various other anions such as F, Cl, Br, I, SCN, ClO, ClO, NO, HPO, SO, and HSO in an acetonitrile solution. In the UV-Vis spectra, a bathochromic shift in the absorption bands of both hydrazones was observed following the addition of cyanide.

Polymicrobial consortia in the pathogenesis of biofilm vaginosis visualized by FISH. Historic review outlining the basic principles of the polymicrobial infection theory.

The manuscript disputes the exclusive mono-infectious way of thinking, which presumes that for every infection only one pathogen is responsible and sufficient, when infectious vectors, close contact and reduced immunity meet. In situations involving heavily colonized anatomical sites such an approach often ends in insoluble contradictions. Upon critical reflection and evaluation of 20 years research on spatial organization of vaginal microbiota it is apparent, that in some situations, pathogens may act and operate in permanent, structurally organized consortia, whereas its individual components may be innocuous and innocent, failing to express any pathogenic effect.

Genetic Determinants of Macrolide and Fluoroquinolone Resistance in and Their Prevalence in Moscow, Russia.

Macrolide (MLR) and fluoroquinolone (FQR) resistance in (MG) has recently become a major problem worldwide. The available data on the prevalence of MLR and FQR in MG in Russia are limited. In this study, we aimed to evaluate the prevalence and pattern of mutations in 213 MG-positive urogenital swabs from patients in Moscow between March 2021 and March 2022.

Clue Cells and Pseudo Clue Cells in Different Morphotypes of Bacterial Vaginosis.

Introduction: Clue cells (epithelial cells heavily covered with adherent bacteria) are an accepted clue to the diagnosis of bacterial vaginosis. However, the exact morphologic criteria of clue cells and bacterial adherence were never elaborated.

Materials And Methods: We investigated adhesive and cohesive patterns of main microbiota groups in vaginal discharge using fluorescence hybridization (FISH).