Publications by authors named "A G Georgiadis"

Effective radiotherapy for cancer treatment requires precise and reproducible positioning of patients at linear accelerators. Assistance systems in digitally networked radiotherapy can help involved specialists perform these tasks more efficiently and accurately. This paper analyses patient positioning systems and develops new knowledge by applying the Design Science Research methodology.

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Article Synopsis
  • Children with cerebral palsy often experience foot deformities, which require precise evaluation for effective treatment and monitoring.
  • This study tested the reliability of a new photo-based assessment tool called the Modified Foot Posture Index (MFPI) among 13 orthopedic surgeons evaluating foot photographs of 20 children with CP.
  • Results indicated that the MFPI exhibits excellent reliability in measuring foot deformities, making it a noninvasive and practical option for clinical and research settings.
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Background: Osteogenesis imperfecta (OI) is a genetic defect in collagen type I, phenotypically characterized by bony fragility and a propensity to high rates of childhood fracture. Fragility fractures in patients with OI have been reported with routine hospital care. In addition, there is a nonzero rate of iatrogenic fracture during orthopaedic surgery directly related to the technical steps of the procedure itself.

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Purpose: To assess the safety and efficacy of AAV5-hRKp.RPGR in participants with retinitis pigmentosa GTPase regulator (RPGR)-associated X-linked retinitis pigmentosa (XLRP).

Design: Open-label, phase 1/2 dose escalation/expansion study (ClinicalTrials.

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