Publications by authors named "A G DuChene"
rVSVΔG-ZEBOV-GP and Ad26.ZEBOV, MVA-BN-Filo are WHO-prequalified vaccination regimens against Ebola virus disease (EVD). Challenges associated with measuring long-term clinical protection warrant the evaluation of immune response kinetics after vaccination.
View Article and Find Full Text PDFOver the course of evolution, land plant mitochondrial genomes have lost many transfer RNA (tRNA) genes and the import of nucleus-encoded tRNAs is essential for mitochondrial protein synthesis. By contrast, plastidial genomes of photosynthetic land plants generally possess a complete set of tRNA genes and the existence of plastidial tRNA import remains a long-standing question. The early vascular plants of the Selaginella genus show an extensive loss of plastidial tRNA genes while retaining photosynthetic capacity, and represent an ideal model for answering this question.
View Article and Find Full Text PDFArticle Synopsis
- rVSVΔG-ZEBOV-GP is a vaccine that helps protect people from the Ebola virus and is the first one to be officially approved for this purpose.
- This study wanted to see how well a booster shot given 18 months after the first vaccine dose helped keep the immune response strong for a longer time.
- Healthy adults who might be at risk of exposure to Ebola participated in the trial, and the results measured their antibody levels 36 months after the first vaccination to compare those who got the booster with those who did not.
Article Synopsis
- Planetary defense research is heavily dependent on understanding the mechanical properties of asteroids, which are challenging to assess from Earth.
- A study of boulders on the asteroid Dimorphos, using data from the DART mission, revealed an estimated internal friction angle of 32.7 ± 2. 5°, indicating they likely formed from impact processing.
- The similarities between Dimorphos boulders and those on other rubble-pile asteroids (Itokawa, Ryugu, and Bennu) suggest a shared formation process and enhance our understanding of asteroid characteristics and the implications for planetary defense strategies.