Publications by authors named "A G Drozd"

So far, it has been proven that benign prostatic hyperplasia (BPH) is strongly associated with inflammation resulting from, i.a. the presence of infectious agent, autoimmune disease, aging process and lipid disorders associated with metabolic syndrome (MetS).

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Article Synopsis
  • Short-chain fatty acids (SCFAs) are metabolites produced by intestinal bacteria from fermented undigested polysaccharides, with key types including acetic, butyric, and propionic acids.
  • The study examined the correlation between SCFA concentrations and gastrointestinal symptoms in infants using fecal samples at various ages, revealing specific associations between butyric acid and symptoms like flatulence and mucus in stool across different stages.
  • By 12 months, gastrointestinal symptoms notably decreased, indicating that while higher levels of butyric and valeric acids can cause issues like gas in early months, they are not linked to intestinal colic, and certain acids may affect defecation and allergies.
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The potential modulation of thyroid inflammatory conditions via a gluten-free diet has been suggested after establishing a link between Hashimoto's thyroiditis (HT) and celiac disease. However, the majority of targeted studies in this field do not support the general recommendation of prescribing a gluten-free diet (GFD) for all HT patients. This study aims to analyze data regarding the impact of a GFD supplemented with eicosapentaenoic (EPA) and docosahexaenoic acid (DHA), along with vegetables, on the course of inflammation involving long-chain fatty acid mediators.

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We studied the radical-binding and antioxidant activities of the alkaloid tryptanthrin (TR) and its new synthetic derivative tryptanthrin oxime (TR-Ox), as well as the cytoprotective activity of TR-Ox under conditions of oxidative stress. The antiradical activity of TR-Ox was revealed in the test of binding with stable chromogen radical 2,2-diphenyl-1-picrylhydrazyl and in the superoxide radical generation test (riboflavin photoreduction reaction with detection by NBT reduction). TR-Ox was inferior to ionol and dihydroquercetin by the antiradical activity.

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