Performance and Psychophysiological Effects of Light-Guided Pacing During a 5000-m Run.

Purpose: In world-class middle- and long-distance running races, a Wavelight signal has recently been used as a pacing guide for setting records. The aim of the present study was to compare performance and psychophysiological effects between light-guided, drafting, and nonassisted pacing conditions in distance runners.

Methods: Fifteen male middle- and long-distance runners of national and regional standard ran three 5000-m time trials in a counterbalanced order with the following pacing distribution: the first 4000 m and last 1000 m were covered at submaximal and maximal intensities, respectively.

Serendipity in Science: 50+ Years of Designed, and Sometimes Lucky, Science.

Normal science is about assessing what is already known about a topic, about what needs to be known, and careful methods to collect the data required to answer the scientific question. It is the mainstay of scientific progress. But sometimes, luck or chance (eg, serendipity) plays a significant role in scientific process.

Quantitative Analysis of the Carpal Tunnel and Its Inner Structures in Primates.

To explore the anatomical factors potentially involved in the high incidence of carpal tunnel syndrome in humans, we have quantified the anatomical variations of the carpal tunnel and its inner structures in humans, non-hominoid primates (monkeys), and hominoid primates (apes). In specimens of six humans, eight monkeys, and three apes, we assessed the size of the carpal tunnel, the tendons of the digit flexor muscles, and the median nerve. We compared the size of the carpal tunnel normalized by the wrist size, and the size of the median nerve and the tendons of the digit flexors normalized by the size of the carpal tunnel.

The development of a whole-cell biosensor enabled the identification of agmatine-producing Hafnia spp. in cheese.

Agmatine, the decarboxylation product of arginine, is the precursor of putrescine - a harmful biogenic amine (BA) - that can accumulate in dairy products via bacterial metabolism involving the agmatine deiminase (AGDI) pathway. This first requires agmatine be produced via the decarboxylation of arginine and it remains unknown which microorganisms are responsible for this prior decarboxylation step. In addition, agmatine, as other BA, plays different physiological roles including those of co-transmitter and neuromodulator.

Changes in choroidal thickness and lamina cribrosa position in subjects with overdipper pattern of arterial pressure.

Introduction: The purpose is to analyze the changes produced in subjects with an overdipper pattern of ambulatory blood pressure monitoring with the aim of understanding the pathophysiology of normal tension glaucoma.

Methods: A cross sectional study was performed in patients exhibiting overdipper and non-overdipper blood pressure patterns, respectively. Different optic parameters were assessed including the analysis of ganglion cell layer (GCL), peripapillary retinal nerve fiber layer (pRNFL) and Bruch's membrane opening-minimum rim width (BMO-MRW), as well as changes produced in choroidal thickness (CT) and lamina cribrosa (LC) position at two different periods of the day (early morning and evening).