Publications by authors named "A Fuat"
Patients with acutely decompensated heart failure (ADHF) are usually admitted to hospital for management. There is growing interest in delivering intravenous (IV) diuretic therapy at home, in the community or at hospital day-care units; the safety and effectiveness of outpatient-based management (OPM) for ADHF has not been established. We conducted a systematic literature review and meta-analysis to investigate the short-term safety and effectiveness of OPM compared with inpatient management (IPM) of ADHF.
View Article and Find Full Text PDFBackground: Loop diuretics are commonly prescribed in the community, not always to patients with a recorded diagnosis of heart failure (HF). The rate of HF events in patients prescribed loop diuretics without a diagnosis of HF is unknown.
Methods: This was a propensity-matched cohort study using data from the Clinical Practice Research Datalink, Hospital Episode Statistics and Office of National Statistics in the UK.
Article Synopsis
- Heart failure (HF) is becoming more prevalent and can lead to serious health issues and increased healthcare costs, but many cases go undetected until severe symptoms appear and hospitalization is needed.
- Researchers are developing a prediction model using electronic health records (EHRs) to estimate the risk of new-onset HF over different time spans (1, 5, and 10 years) by applying various methods like logistic regression and machine learning.
- The study has received ethical approval and aims to publish its findings in a peer-reviewed journal, with the trial registered on Clinical Trials.gov and a systematic review on PROSPERO.
Aims: The aim of the study was to assess the real-world feasibility, acceptability, and impact of an integrated risk tool for cardiovascular disease (CVD IRT, combining the standard QRISK®2 risk algorithm with a polygenic risk score), implemented within routine primary practice in the UK National Health Service.
Methods And Results: The Healthcare Evaluation of Absolute Risk Testing Study (NCT05294419) evaluated participants undergoing primary care health checks. Both QRISK2 and CVD IRT scores were returned to the healthcare providers (HCPs), who then communicated the results to participants.