Publications by authors named "A Froidure"

Background: Interstitial lung disease (ILD) is rarer in children (chILD) than adults, but with increasing diagnostic awareness, more cases are being discovered. chILD prognosis is often poor, but increasing numbers are now surviving into adulthood.

Aim: To characterize chILD-survivors and identify their impact on adult-ILD centers.

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  • * The findings indicate that a significant number of patients achieved better control of their asthma symptoms after changing their treatment.
  • * The results suggest that switching biologics can be an effective strategy for managing severe asthma.
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  • Nearly all medications can cause drug-induced liver injury (DILI), which often has unpredictable and poorly understood reactions.
  • Pirfenidone, an antifibrotic drug for idiopathic pulmonary fibrosis, can elevate liver enzymes but usually doesn't require stopping the medication.
  • This case study discusses a 70-year-old woman who experienced acute hepatocellular hepatitis due to pirfenidone, emphasizing the importance of early detection and reporting of DILI.
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Repurposing anticancer drugs to vascular malformations has significantly improved patient outcomes. Complex Lymphatic Anomalies (CLA) are part of the spectrum of lymphatic malformations (LMs) that share similar oncogenic mutations to cancer. We report the case of a young patient with highly symptomatic CLA who was initially treated with sirolimus, due to the frequent involvement of the PI3K-AKT-mTOR pathway in CLA pathogenesis.

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