Publications by authors named "A Fritzler"
Article Synopsis
- * It involved 496 healthcare professionals from three hospitals, analyzing hair cortisol levels as a chronic stress biomarker and finding significant associations between high cortisol levels, workload, age, and emotional exhaustion.
- * The research concludes that burnout in 11% of participants correlates with increased stress and lower social support, emphasizing the need for targeted interventions to enhance healthcare workers' well-being.
Article Synopsis
- Metabolic syndrome (MS) negatively impacts reproductive health in female mice, leading to issues like disrupted estrous cycles and impaired reproductive success.
- In the study, mice on a high-fat diet showed signs of MS, such as insulin resistance and hormonal imbalances, which affected their endometrial health and reproductive outcomes.
- Treatment with metformin improved these reproductive issues by normalizing hormone levels and restoring proper endometrial function, suggesting potential benefits for women with MS seeking to enhance reproductive health.
The aim of the study was to evaluate adrenal axis hyperactivation measuring hair cortisol levels, and its influence on the relationship among metabolic parameters, inflammation markers and androgens in adult women with PCOS. 44 women (18-34 years) with PCOS diagnosis and a control group of 49 healthy women (19-35 years) were included. In both gropus body mass index (BMI) was calculated and waist circumference (WC) was measured.
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- A new automated method has been developed for measuring cortisol levels in hair samples, marking the first procedure of its kind.
- The study analyzed hair samples from 286 individuals, establishing normal cortisol reference values based on data from 213 low-stress individuals, which averaged at 55 pg/mg.
- Stressed individuals had significantly higher hair cortisol levels, with a median of 250 pg/mg, but hair dye did not impact cortisol measurements, indicating the method's strong analytical performance.