Two Blatter Radicals Face-to-Face: A Constrained Diradical Architecture.

Cofacial arrangement of two Blatter radicals enforced by the -naphthalene scaffold represents a new approach to stable diradicals with strong through-space interactions. Two stereoisomers of the naphthalene-diradicals, and , are investigated by XRD, VT-EPR, UV-vis, electrochemical, kinetic, and DFT methods. In solutions, both stereoisomers exist as open-shell singlets with Δ = -3.

Sun exposure and challenges of sun protection in adolescents and young adults: A prevalence observational study.

The present study aimed to explore the adherence to and efficiency of skin protection measures among teenagers and young adults. The present study investigated the reasons for sun exposure and the obstacles impeding sun protection. In the summer of 2023, a self-reported questionnaire was posted on the social media account of two high schools, a university, some industrial companies and among the teenage children of a dermatology clinic.

[-BH-1-CN-10-Azinium] Anions: Photoactive Heteroditopic Ligands for Metal Complexes.

A new class of rigid, photoactive heteroditopic anionic ligands based on the 1,10-disubstituted [-BH] anion was designed and six of these compounds were obtained from [-BH] in three steps with yields in the range of 25-30%. The design includes two apical substituents, a metal coordinating cyano group and an azinium (4-cyanopyridinium, 4,4'-bipyridinium, pyrazinium, pyrimidinium, and pyridazinium), which provides a secondary binding site. The azinium substituent is involved in an efficient intramolecular charge transfer process and compensates one of the two delocalized negative charges of the boron cluster.

[-BH-10-PhI-1-COOH] Anion: An Intermediate for Functional Anionic Carboxylate Ligands.

A potentially general intermediate, [-BH-10-PhI-1-COOH], for a class of functional anionic carboxylic acids, [-BH-10-X-1-COOH], was obtained in four steps and 26% overall yield from [-BH]. It was converted to the pyridinium derivative (X = CHN) and subsequently to coordination complexes with (phen)Cu and (phen)Zn ions. Both the acid and Zn(II) complex exhibit a cage-to-pyridine charge-transfer band.

Discovery and Structure-Activity Relationship of Cadazolid: A First-In-Class Quinoxolidinone Antibiotic for the Treatment of Infection.

() is one of the leading causes of healthcare-associated infections worldwide. The increasing incidence of strains resistant to currently available therapies highlights the need for alternative treatment options with a novel mode of action. Oxazolidinones that are connected to a quinolone moiety with a pyrrolidine linker, such as compound , are reported to exhibit potent broadspectrum antibacterial activity.