Publications by authors named "A Franco-Obregon"

Article Synopsis
  • * The study aims to explore if combining standard exercises with pulse electromagnetic field therapy can enhance stability and reduce muscle weakness in patients with chronic ankle instability.
  • * A randomized trial with 48 participants will compare the effects of active therapy with a placebo over 8 weeks, with evaluations conducted at multiple follow-up points.
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: Doxorubicin (DOX) is commonly used as a chemotherapeutic agent for the treatment of breast cancer. Nonetheless, its systemic delivery via intravenous injection and toxicity towards healthy tissues commonly result in a broad range of detrimental side effects. Breast cancer severity was previously shown to be correlated with TRPC1 channel expression that conferred upon it enhanced vulnerability to pulsed electromagnetic field (PEMF) therapy.

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Background: Pulsed electromagnetic field (PEMF) therapy is a potential nonoperative treatment for Achilles tendinopathy, but the current published literature on its effects is sparse.

Purpose: To evaluate the therapeutic efficacy of PEMF therapy and eccentric exercise for Achilles tendinopathy.

Study Design: Randomized controlled trial; Level of evidence, 1.

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Article Synopsis
  • Osteoarthritis of the knee is a prevalent condition in older adults, prompting research into effective treatments such as home exercises and pulsed electromagnetic field (PEMF) therapy to alleviate symptoms.
  • A study involving 60 patients found that those receiving both PEMF and exercise showed significant improvements in muscle strength and functional measures like gait speed and pain levels compared to those who only did home exercises.
  • The combination therapy particularly benefited older patients and highlighted gender differences in outcomes, indicating a promising approach for enhancing quality of life in those with knee osteoarthritis.
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Transient receptor potential (TRP) channels are broadly implicated in the developmental programs of most tissues. Amongst these tissues, skeletal muscle and adipose are noteworthy for being essential in establishing systemic metabolic balance. TRP channels respond to environmental stimuli by supplying intracellular calcium that instigates enzymatic cascades of developmental consequence and often impinge on mitochondrial function and biogenesis.

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