The methods for removal of direct oral anticoagulants and heparins to improve the monitoring of hemostasis: a narrative literature review.

The assessment of hemostasis is necessary to make suitable decisions on the management of patients with thrombotic disorders. In some clinical situations, for example, during thrombophilia screening, the presence of anticoagulants in sample makes diagnosis impossible. Various elimination methods may overcome anticoagulant interference.

Effects of two recovery procedures after a football game on sensory and biochemical markers.

Aim: The aim of this study was to investigate recovery processes on pressure pain sensitivity and blood indicators in professional football players after three different post-game training modalities: standard recovery training, no physical activity, delayed onset muscle soreness reduction training.

Methods: Eleven male football field players participated in the present study. The experiment was performed in three sessions over three weeks after three football league games.

The effect of variant chromosomes on reproductive fitness in man.

Reproductive fitness of carriers of heterochromatic variants of the human karyotype was found to be normal. The method was based on a comparison between known carriers and known non-carriers from the same pedigree in respect of live births, generation time and survival of offspring to reproductive age. A subset of the data had been included in an earlier study in which reproductive fitness of carriers was found to be significantly reduced.

A study of familial factors in Alzheimer's disease.

Data on the families of 74 probands with autopsy-proven Alzheimer's disease did not support the hypothesis, advanced by Heston and co-workers, of a familial association between Alzheimer's disease, Down's syndrome and immunoproliferative disorders. However, there are difficulties of interpreting negative conclusions in this type of study, particularly those resulting from small sample size and the impossibility of tracing all relatives; only the data for immunoproliferative disorders are incompatible with the hypothesis, those for Down's syndrome being too few to be informative. The incidence of presenile dementia among the first-degree relatives of probands was raised, as in many previous studies, and was consistent with a simple polygenic model.