Publications by authors named "A Floe"
Objectives: To investigate the association between quantitative T-SPOT.TB values and the risk of incident and prevalent tuberculosis disease (TBD), identify risk factors, and evaluate test accuracy.
Methods: This retrospective cohort study followed patients tested consecutively with T-SPOT.
Article Synopsis
- A study compared the effects of extra-fine particle inhaled corticosteroids (ICS) to standard particle size ICS on patients with chronic obstructive pulmonary disease (COPD) from 2010 to 2017, focusing on exacerbations needing hospitalization and overall mortality rates.
- Of the nearly 40,500 patients analyzed, the results showed that extra-fine particle ICS did not significantly lower the risk of hospitalizations or all-cause mortality compared to standard ICS; however, a subgroup of patients using pressurized metered dose inhalers (pMDIs) did report reduced risks.
- The findings suggest that while extra-fine particle ICS may not generally offer protective benefits, they could be beneficial for specific patients
Evidence on mortality rates and causes of death associated with extrapulmonary nontuberculous mycobacteria (NTM) infection is limited. This nationwide register-based study in Denmark used diagnostic codes to match adult patients with extrapulmonary NTM infection 1:4 to controls. During 2000–2017, we identified 485 patients, who had significantly more comorbidities than controls.
View Article and Find Full Text PDFIn this case report, we present case reports for two nurses, both working in departments of respiratory medicine, who developed tuberculosis (TB). For each individual case, whole genome sequencing (WGS) revealed only one specific match within a genomic distance of <6 single-nucleotide polymorphisms. The subsequent epidemiological investigations confirmed that both nurses had relevant exposures to their corresponding match 1139 and 1704 days before presenting with TB symptoms, respectively.
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