Publications by authors named "A Flieger"
Article Synopsis
- Shiga-toxin-producing E. coli (STEC) are harmful bacteria that can cause severe illnesses like diarrhea and kidney failure, making quick detection crucial but difficult.
- A new rapid test has been developed using synthetic DNA substrates that produce a fluorescent signal when cleaved by Shiga toxins, allowing for easier identification of STEC.
- In testing 94 clinical strains, including various STEC serotypes, this assay proved effective for immediate detection of Shiga toxins, potentially enhancing outbreak response and treatment strategies.
A food-borne outbreak with about 200 Umbilo cases occurred mainly between July and September 2024 in several European countries. Collaborative work between outbreak teams in Germany, Austria and Denmark, including epidemiological and microbiological investigations, allowed to rapidly identify rocket salad as the likely infection vehicle. Umbilo was detected in rocket salad, and later in baby spinach.
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- Nontyphoidal Salmonella (NTS) is a major cause of invasive infections among children under 5 in sub-Saharan Africa, with asymptomatic fecal shedding possibly facilitating human-to-human transmission, particularly in low-resource areas.
- This study involved 3,293 children and healthy individuals in Nairobi, revealing a 1.52% prevalence of NTS, and 31% of children with a previous NTS infection exhibited asymptomatic shedding post-treatment, with some shedding the same strain as during their illness.
- The findings suggest a likely connection between asymptomatic shedding and the transmission of NTS, supporting the idea that introducing a vaccine could help mitigate these infections in vulnerable populations.*
Article Synopsis
- Foodborne illnesses like listeriosis, caused by the Listeria bacteria, are a big worry for public health, especially during outbreaks.
- Scientists collected and studied over 1800 Listeria samples from patients in Germany to understand how the bacteria spread and caused infections.
- They found that many infection clusters lasted a long time and could affect people in different regions, with some bacteria types being more harmful than others.
Enteroaggregative Escherichia coli (EAEC) strains including those of serogroup O111 are important causes of diarrhea in children. In the Czech Republic, no information is available on the etiological role of EAEC in pediatric diarrhea due to the lack of their targeted surveillance. To fill this gap, we determined the proportion of EAEC among E.
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