Publications by authors named "A Flaus"
Presurgical evaluation aims to localize the seizure onset zone (SOZ) for a tailored resection. Interictal [F]fluorodeoxyglucose PET is now an established test to lateralize and/or localize the SOZ, particularly if MR imaging is negative or if the noninvasive assessment shows discrepancies. PET can show hypometabolic areas associated with SOZ and the potential altered metabolic brain networks.
View Article and Find Full Text PDFDeep Convolutional Backbone Comparison for Automated PET Image Quality Assessment.
IEEE Trans Radiat Plasma Med Sci
November 2024
Article Synopsis
- Pretraining deep convolutional networks using natural images can enhance medical imaging analysis, particularly given the scarcity of annotated medical data.
- The study compared 18 different pretrained backbone networks for evaluating the quality of PET brain scans, using data from multiple patients and testing against clinical quality metrics.
- Results indicated that using residual units in backbone architectures improved performance, with many networks achieving a mean-absolute-error below 0.5, highlighting the potential of over-parameterization for automated image quality assessments.
Moonlighting on the Fasciola hepatica tegument: Enolase, a glycolytic enzyme, interacts with the extracellular matrix and fibrinolytic system of the host.
PLoS Negl Trop Dis
August 2024
Article Synopsis
- Enolase is an important enzyme in our bodies that helps convert energy during processes like glycolysis and gluconeogenesis.
- Some types of parasites and bacteria have a special kind of enolase that helps them stick to host tissues, making it easier for them to cause infections.
- Researchers are studying enolase from the Fasciola hepatica parasite, which could help us understand how it invades its host and possibly lead to better treatments for the diseases it causes.
Article Synopsis
- F-FDG PET/CT imaging's effectiveness for detecting liver metastasis can be affected by various factors, including the type of PET technology, lesion size, and body mass index (BMI).
- A study involving 192 patients evaluated these factors and found that TOF PET/CT technology had higher sensitivity, particularly for larger lesions.
- Specifically, lesions smaller than 10 mm and higher BMI were associated with reduced sensitivity, while factors like age, sex, and liver density showed no significant effect.
Purpose: Data published in the literature concerning the doses received by fetuses exposed to a 18 F-FDG PET are reassuring but were obtained from small and heterogeneous cohorts, and very few data are available concerning the fetal dose received after exposure to both PET and CT. The present study aimed to estimate the fetal dose received following a PET/CT exposure using methods that include anthropomorphic phantoms of pregnant women applied on a large cohort.
Patients And Methods: This retrospective multicenter study included 18 pregnant patients in the second and third trimesters.