Publications by authors named "A Ficheux"

Background: The causes of pruritus are multiple and commonly classified into six different categories: dermatological, systemic, neuropathic, psychogenic, mixed and idiopathic. In clinical practice, psychogenic and neurogenic mechanisms tend to be separated in the etiological diagnosis of neuropathic or psychogenic disorders; nevertheless, studies investigating the respective psychogenic and neurogenic components are lacking.

Objective: The main objective of this work was to highlight the differences and potential common characteristics between psychogenic pruritus and neuropathic pruritus.

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  • Seaweeds are rich in iodine and can accumulate contaminants, making them important in evaluating dietary risks for the French population.
  • This study assessed dietary exposure to iodine and trace elements from seaweeds, finding that while they contribute significantly to iodine intake (up to 33%), they only minimally contribute to total dietary exposure to harmful contaminants like cadmium, mercury, and arsenic.
  • New recommended maximum limits for these contaminants in seaweeds were proposed to ensure safety, significantly lower than current levels (e.g., 1 mg/kg for cadmium).
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  • Pruritus, particularly aquagenic pruritus (AP), is a common symptom among patients with myeloproliferative neoplasms (MPN), affecting nearly half of those surveyed in the study.
  • The study analyzed 1444 questionnaires from 504 MPN patients and found that those experiencing pruritus had a higher symptom burden and progression to more severe forms of the disease.
  • Treatment with ruxolitinib and hydroxyurea was noted to be most effective in alleviating AP symptoms, highlighting the need for regular assessment of pruritus in MPN patients due to its significant impact on their overall health.
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Introduction: Small fiber neuropathies (SFNs) are disorders of skin nerve endings inducing pruritus, burning pain, numbness, and paresthesia. The aims of this study were to search for putative etiologies of SFN and their occurrence in a cohort of patients and to compare patients with SFN to a group of patients without SFN to highlight potential factors associated with SFN.

Methods: This study was observational, retrospective, and monocentric.

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