Publications by authors named "A Fernandez-Cruz"
Background: Recent data support F-FDG PET-CT for the management of infections in immunocompromised patients, including invasive fungal infection (IFI). However, its role is not well established in clinical practice. We performed an international survey to evaluate the knowledge of physicians about the usefulness of F-FDG PET-CT in IFI, in order to define areas of uncertainty.
View Article and Find Full Text PDFHow can we optimize the diagnostic and therapeutic approach to pneumonia? Expert opinion-based recommendations.
Enferm Infecc Microbiol Clin (Engl Ed)
October 2024
Article Synopsis
- - Pneumonia is a common and serious infectious disease, significantly impacting mortality rates and healthcare resources.
- - The OPENIN Group, comprised of specialists in Infectious Diseases and Microbiology, focuses on improving clinical processes related to pneumonia diagnosis and treatment through a review of existing scientific research.
- - The group's initial meeting in October 2023 addressed optimizing pneumonia diagnosis, possibly reducing antibiotic treatment duration, and exploring the use of immunomodulatory strategies like steroids, leading to expert recommendations based on their findings.
Article Synopsis
- A study analyzed the management and mortality outcomes of nontuberculous mycobacterial (NTM) infections in solid organ transplant (SOT) recipients, focusing on data from 2008 to 2018.
- Out of 85 patients with NTM infections and 169 matched controls, one-year mortality was significantly higher in the infected group (20%) compared to controls (3%), particularly among those who had lung transplants.
- Factors like time to treatment and changes in immunosuppression levels did not show a direct correlation with mortality rates among the patients.
Febrile neutropenia (FN) is a complication of hematologic malignancy therapy. An early diagnosis would allow optimization of antimicrobials. The F-FDG-PET-CT may be useful; however, its role is not well established.
View Article and Find Full Text PDFEfficacy and safety of antiviral plus anti-spike monoclonal antibody combination therapy vs. monotherapy for high-risk immunocompromised patients with mild-to-moderate SARS-CoV2 infection during the Omicron era: A prospective cohort study.
Int J Antimicrob Agents
March 2024
Introduction: Antivirals and monoclonal antibodies lower the risk of progression in immunocompromised patients. However, combination therapy with both types of agents has not been studied.
Patients And Methods: This was a single-centre, prospective, cohort study.