Publications by authors named "A Fernand Koffi"

In Côte d'Ivoire, there is a high intensity of pyrethroid resistance in malaria vectors which may threaten successful vector control. Molecular studies of the target site mutation in the voltage-gated sodium channel (VGSC) show that the gene frequencies of these mutations are high, widely spread across Côte d'Ivoire, and even fixed in some areas. To further characterize insecticide resistance in Côte d'Ivoire beyond target site mutations, the metabolic resistance mechanism was explored.

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Background: Ensuring healthcare services are equipped to offer; emergency obstetric and newborn care (EmONC) is crucial for improving the quality of maternal and newborn care in low- and middle-income countries. We assessed the temporal trends of the availability and readiness of the healthcare system to provide EmONC in Burkina Faso.

Methods: We analyzed the data from three national health facilities surveys, conducted in 2014, 2016 and 2018, using the WHO Service Availability and Readiness Assessment tool.

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Article Synopsis
  • The study in Bouaké, Côte d'Ivoire, assessed how common asymptomatic and subpatent P. falciparum infections are and compared the effectiveness of three diagnostic tests (light microscopy, rapid diagnostic tests, and quantitative PCR).
  • Out of 2313 participants, 97.2% were asymptomatic, with high prevalence rates found; particularly in school-age children, while subpatent infections were more common in older individuals (≥15 years).
  • The findings suggest that traditional tests only detect high-density infections, and none of the tested samples showed deletions in the pfhrp2 gene, indicating a need for focused malaria reduction strategies in urban areas.
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Treatment of livestock with endectocides such as ivermectin is viewed as a complementary vector control approach to address residual transmission of malaria. However, efficacy of this treatment may vary between animal species. Hence, our purpose was to investigate the effects of ivermectin treatments of common livestock species on life history traits of the opportunistic malaria vector Anopheles coluzzii.

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Background: The World Health Organization advocates integrating neglected tropical diseases (NTDs) into common delivery platforms to combat them in resource-constrained settings. However, limited literature exists on the benefits of integration. This study examines the feasibility and impact of adding skin screening to a mass drug administration (MDA) campaign in Côte d'Ivoire.

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