Publications by authors named "A Fauconnier"
Article Synopsis
- Vulvar cancer primarily affects older women and requires surgical treatment, with guidelines emphasizing the importance of negative histological margins.
- A study analyzed the impact of patient age on surgical outcomes, finding that older patients (≥65 years) had larger tumors but similar rates of negative excision margins compared to younger patients (<65 years).
- Results indicated that younger patients experienced better recurrence-free survival and were more likely to undergo revision surgery despite the older group receiving more radical surgery.
Article Synopsis
- Conjugative plasmids, like those in IncC, prevent the entry of similar plasmids to maintain stability within the host cell through mechanisms like entry and surface exclusion.
- The study identified a new exclusion factor, Sfx, which is necessary for preventing related plasmids from entering a host, and Sfx operates differently from previously known exclusion factors.
- Investigations revealed that Sfx is expressed at higher levels than another factor, eexC, and that the specificity of surface exclusion is mediated by the adhesin TraN in the donor plasmid, contributing to the incompatibility between IncA and IncC plasmids.
Vaginal microbiota stability over 18 months in young student women in France.
Eur J Clin Microbiol Infect Dis
December 2024
Purpose: Non-optimal vaginal microbiota lacking lactobacilli and comprising a wide array of anaerobic bacteria, typified by community state type (CST) IV, have been associated with adverse gynecological and pregnancy outcomes. Here, we investigate the stability of the vaginal microbiota sampled every 6 months over 18 months and how samples distantly collected combined with exposures could provide insight on future microbiota compositional changes.
Methods: Vaginal microbiota dynamics were analyzed in 241 female students aged 18-24 years and negative for Chlamydia trachomatis and Neisseria gonorrhoeae.
Research Question: What is the impact of ethanol sclerotherapy of endometriomas prior to IVF/ICSI on pregnancy rates?
Design: We reviewed women with endometrioma(s) larger than 25 mm having IVF/ICSI cycles. All patients with a history of ovarian cystectomy were excluded. Two groups were compared: patients who had transvaginal ethanol sclerotherapy of their endometrioma(s) before ovarian stimulation and patients whose endometrioma(s) were left in situ (untreated) at the time of IVF/ICSI (control group).
Objective: Vulvar cancer is a rare pathology affecting mainly elderly women. This study aims to evaluate the impact of age on tumor size in vulvar cancer.
Material And Methods: This was a multicenter retrospective observational study carried out between January 1, 1998, and December 31, 2020, in patients operated on for vulvar cancer.