Publications by authors named "A Farge"
A second autologous stem-cell transplantation (ASCT2) is considered for relapsed multiple myeloma (RMM) patients showing prolonged response after a first ASCT. However, given breakthrough treatments like anti-CD38 and immunotherapy, its role remains debated. We conducted a real-life study in 10 French centers (1996-2017) involving 267 RMM patients receiving ASCT2.
View Article and Find Full Text PDFThis prospective study aimed to investigate the prognostic effect of sarcopenia, geriatric, and nutritional status in older patients with diffuse large B-cell lymphoma (DLBCL). Ninety-five patients with DLBCL older than 70 years who were treated with immunochemotherapy were included. The lumbar L3 skeletal muscle index (L3-SMI) was measured by computed tomography at baseline, and sarcopenia was defined as low L3-SMI.
View Article and Find Full Text PDFAortic stenosis in patients with previous valve-sparing root replacement represents a challenge, given the substantial morbidity and mortality rates in case of reoperation. Here, we present the case of a patient with late severe aortic stenosis 12 years after valve-sparing aortic root replacement. He was successfully treated by transapical aortic valve implantation.
View Article and Find Full Text PDFArticle Synopsis
- The study examines T-cell immunological reconstitution in 106 adults undergoing haploidentical hematopoietic cell transplantation (Haplo-HCT) and highlights a lack of comprehensive data in this area.
- Findings reveal that while conventional T cell counts are similar between Haplo-HCT recipients and controls by Day 30, γδ and Vδ2 T-cell counts are significantly lower in Haplo-HCT patients, and this persists up to Day 360.
- The research concludes that delayed reconstitution of γδ T cells is linked to a higher risk of increasing Epstein-Barr virus (EBV) viral load post-transplant.